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Laband Syndrome

Abstract

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Synonyms of Laband Syndrome

  • Gingival Fibromatosis, Abnormal Fingers, Nails, Nose, Ear, Splenomegaly
  • Zimmermann-Laband Syndrome
  • ZLS

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Laband syndrome, also known as Zimmerman-Laband syndrome, is an extremely rare genetic disorder characterized by abnormalities of the head and facial (craniofacial) area and the hands and feet. Most children with this disorder have abnormally large gums (gingival fibromatosis). Overgrown gums may affect the ability to chew, swallow, and/or speak. In addition, affected infants may exhibit abnormally long, thin fingers and toes and/or deformed (dysplastic) or absent nails at birth. In some cases, mental retardation may also be present. In most cases, Laband syndrome is believed to be inherited as an autosomal dominant trait. However, evidence of autosomal recessive inheritance has also been reported.

Organizations related to Laband Syndrome

(Please note that some of these organizations may provide information concerning certain conditions potentially associated with this disorder [e.g., dental abnormalities, mental retardation, etc.].)

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