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Gastritis, Giant Hypertrophic

Abstract

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Synonyms of Gastritis, Giant Hypertrophic

  • Gastroenteropathy, Protein Losing
  • Giant Hypertrophy of the Gastric Mucosa
  • Hypertrophic Gastropathy

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Giant hypertrophic gastritis (GHG) is a general term for inflammation of the stomach due to the accumulation of inflammatory cells in the inner wall (mucosa) of the stomach resulting in abnormally large, coiled ridges or folds that resemble polyps in the inner wall of the stomach (hypertrophic gastric folds). GHG encompasses a collection of disorders. The symptoms of GHG may vary from case to case. The exact cause of GHG is unknown.

There is considerable confusion and contradiction in the medical literature regarding disorders involving large gastric folds. GHG is often used as a synonym for Menetrier disease. However, Menetrier disease is not a true form of gastritis. A diagnosis of Menetrier disease should indicate massive overgrowth of mucous cells (foveola) in the gastric mucosa (foveolar hyperplasia) and minimal inflammation. Foveolar hyperplasia results in large gastric folds. Because inflammation is minimal, Menetrier disease is classified as a form of hyperplastic gastropathy and not a form of gastritis. Some researchers believe that GHG and Menetrier disease may be variants of the same disorder or different parts of one disease spectrum.

Organizations related to Gastritis, Giant Hypertrophic

Please note that some of these organizations may provide information concerning certain conditions potentially associated with this disorder.

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