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Henoch-Schönlein Purpura

Abstract

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Synonyms of Henoch-Schönlein Purpura

  • Allergic Purpura
  • Allergic Vasculitis
  • Anaphylactoid Purpura
  • Hemorrhagic Capillary Toxicosis
  • HSP
  • Leukocytoclastic Vasculitis
  • Nonthrombocytopenic Idiopathic Purpura
  • Peliosis Rheumatica
  • Rheumatic Purpura
  • Schonlein-Henoch Purpura

Disorder Subdivisions

  • Henoch's Purpura
  • Schonlein's Purpura

General Discussion

Henoch-Schönlein purpura is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease. It is the most common form of childhood vascular inflammation (vasculitis) and results in inflammatory changes in the small blood vessels. The symptoms of Henoch-Schönlein purpura usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain, and joint pain. Red or purple spots typically appear on the skin (petechial purpura). Inflammatory changes associated with Henoch-Schönlein purpura can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord (central nervous system).

In one form of the disorder, termed Schönlein's purpura, the skin and joints are affected but the gastrointestinal tract is not. In another form, known as Henoch's purpura, affected individuals have purplish spots on the skin and acute abdominal problems. People with Henoch's purpura are not affected by joint disease.

The exact cause of Henoh-Schönlein purpura is not fully understood, although research suggests that it may be an autoimmune disease or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).

Organizations related to Henoch-Schönlein Purpura

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