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Sporadic Inclusion Body Myositis

Abstract

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NORD is very grateful to Steven A Greenberg, MD, Associate Professor of Neurology, Harvard Medical School, for assistance in the preparation of this report.

Synonyms of Sporadic Inclusion Body Myositis

  • IBM

Disorder Subdivisions

  • Inflammatory Myopathy

General Discussion

Sporadic inclusion body myositis (sIBM) is an acquired progressive muscle disorder that becomes apparent during adulthood. The symptoms and progression of sIBM vary from one person to another. In most cases, sIBM is characterized by progressive weakness and degeneration (atrophy) of the muscles especially those of the arms and the legs. sIBM can progress to cause severe disability. The exact cause of the disorder is unknown and the muscle tissue of affected individuals shows both inflammatory and degenerative changes. sIBM is a complex disorder and, most likely, multiple factors including genetic, immunological and environmental ones in combination all play a role in its development.

Organizations related to Sporadic Inclusion Body Myositis

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