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Amniotic Band Syndrome

Abstract

You are reading a NORD Rare Disease Report Abstract. NORD’s full collection of reports on over 1200 rare diseases is available to subscribers (click here for details). We are now also offering two full rare disease reports per day to visitors on our Web site.

NORD is very grateful to Lewis B. Holmes, MD, Emeritus Chief, Genetics Unit, MassGeneral Hospital for Children, and Professor of Pediatrics, Harvard Medical School, for assistance in the preparation of this report.

Synonyms of Amniotic Band Syndrome

  • ABS
  • amnion rupture sequence
  • amniotic bands
  • amniotic band sequence
  • amniotic deformity, adhesions, mutilations (ADAM) complex
  • congenital constriction rings
  • constriction band syndrome
  • limb body wall complex
  • Streeter anomaly
  • Streeter bands
  • Streeter dysplasia

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Amniotic band syndrome is a well-known condition potentially associated with a variety of different birth defects. It is important to note that no two cases of amniotic band syndrome are exactly alike and that the associated symptoms are highly variable. The severity of amniotic band syndrome can range from a single, isolated finding to multiple, disfiguring complications. The arms and legs are most often affected. The head and face and, in some cases, various internal organs can also be affected. The exact cause of amniotic band syndrome is unknown and controversial. Two main theories have been proposed to explain the development of the disorder. One theory attributes the disorder to causes that arise internally within the fetus (intrinsic theory); the other theory attributes the disorder to causes acting upon the fetus externally (extrinsic theory). It is likely that both internal and external factors can cause amniotic band syndrome, and that the cause of the disorder in one infant may be different from the cause in another infant.

Organizations related to Amniotic Band Syndrome

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