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Simple Pulmonary Eosinophilia

Abstract

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NORD is very grateful to Evans Fernandez Perez, MD, MS, Autoimmune and Interstitial Lung Disease Center, Division of Pulmonary and Critical Care Medicine, National Jewish Health, for assistance in the preparation of this report.

Synonyms of Simple Pulmonary Eosinophilia

  • Loeffler syndrome
  • Löffler syndrome

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Summary
Simple pulmonary eosinophilia (SPE), also known as Loeffler syndrome, is a rare, temporary (transient) respiratory disorder characterized by the accumulation of eosinophils in the lungs (pulmonary eosinophilia). Eosinophils are a type of white blood cell and are part of the immune system. They are usually produced in response to allergens, inflammation or infection and are particularly active in the respiratory tract. Most cases of SPE are believed to be due to an allergic reaction to drugs and infection (especially parasitic ones). SPE usually ranges in severity from individuals who do not develop any symptoms (outside of eosinophilia) to individuals who develop mild symptoms. In extremely rare cases, more significant complications can occur. Generally, no specific therapy is required as symptoms usually go away spontaneously without treatment.

Introduction
Simple pulmonary eosinophilia was first described in the medical literature in 1932. It is classified as a form of eosinophilic lung disease, a large group of interstitial lung diseases. SPE is considered a benign, self-limiting disorder.

Simple Pulmonary Eosinophilia Resources

Please note that some of these organizations may provide information concerning certain conditions potentially associated with this disorder.

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