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Fox Fordyce Disease

Abstract

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NORD is very grateful to Timothy H. McCalmont, MD, Departments of Pathology and Dermatology, University of California, San Francisco, for assistance in the preparation of this report.

Synonyms of Fox Fordyce Disease

  • apocrine duct occlusion
  • apocrine miliaria

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Fox-Fordyce disease is a rare skin disorder that primarily affects women. The disorder is characterized by intense itching especially in the underarm area, the pubic area and around the nipples. In Fox-Fordyce disease abnormalities affecting the apocrine sweat glands causes inflammation, and enlargement of the glands and the characteristic intense itching. Skin near an affected area may become darkened and dry and multiple, small, raised bumps (papules) may develop. Hair follicles in the affected area can become secondarily damaged, resulting in hair loss. The exact cause of Fox-Fordyce disease is unknown.

Organizations related to Fox Fordyce Disease

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