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Copyright 1986, 1989, 1994, 2003, 2007
Synonyms of Agranulocytosis, Acquired
- Agranulocytic Angina
- Granulocytopenia, Primary
- Neutropenia, Malignant
Disorder Subdivisions
General Discussion
Acquired agranulocytosis is a rare, drug-induced blood disorder that is characterized by a severe reduction in the number of white blood cells (granulocytes) in the circulating blood. The name granulocyte refers to grain-like bodies within the cell. Granulocytes include basophils, eosinophils, and neutrophils.
Acquired agranulocytosis may be caused by a variety of drugs. However, among the drugs to which a patient may be sensitive are several used in the treatment of cancer (cancer chemotherapeutic agents) and others used as antipsychotic medications (e.g., clozapine). The symptoms of this disorder come about as the result of interference in the production of granulocytes in the bone marrow.
People with acquired agranulocytosis are susceptible to a variety of bacterial infections, usually caused by otherwise benign bacteria found in the body. Not infrequently, painful ulcers also develop in mucous membranes that line the mouth and/or the gastrointestinal tract.
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Organizations related to Agranulocytosis, Acquired
- Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg MD 20898-8126
Phone #: 301-251-4925
800 #: 888-205-2311
e-mail: ordr@od.nih.gov
Home page: http://rarediseases.info.nih.gov/Default.aspx
- MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay WI 54301-1243
Phone #: 920-336-5333
800 #: 877-336-5333
e-mail: mums@netnet.net
Home page: http://www.netnet.net/mums/
- Madisons Foundation
PO Box 241956
Los Angeles CA 90024
Phone #: 310-264-0826
800 #: N/A
e-mail: getinfo@madisonsfoundation.org
Home page: http://www.madisonsfoundation.org
- NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda MD 20824-0105
Phone #: 301-592-8573
800 #: --
e-mail: nhlbiinfo@rover.nhlbi.nih.gov
Home page: N/A
- National Neutropenia Network
PO Box 1693
Brighton MI 48116
Phone #: 810-229-5797
800 #: N/A
e-mail: leereeves99@gmail.com
Home page: http://www.neutropenianet.org
- Neutropenia Support Association, Inc.
971 Corydon Avenue
P.O. Box 243
Winnepeg
Manitoba None R3M 3S7
Phone #: 204-489-8454
800 #: 800-663-8876
e-mail: stevensl@neutropenia.ca
Home page: http://www.neutropenia.ca
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