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Anemia, Megaloblastic

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Synonyms of Anemia, Megaloblastic
  • Folate Deficiency Anemia
  • Folic Acid Deficiency Anemia
  • Vitamin B12 Deficiency Anemia

Disorder Subdivisions



General Discussion
Megaloblastic anemia is a condition in which the bone marrow produces unusually large, structurally abnormal, immature red blood cells (megaloblasts). Bone marrow, the soft spongy material found inside certain bones, produces the main blood cells of the body -red cells, white cells, and platelets. Anemia is a condition characterized by the low levels of circulating, red blood cells. Red blood cells are released from the marrow into the bloodstream where they travel throughout the body delivering oxygen to tissue. A deficiency in healthy, fully-matured red blood cells can result in fatigue, paleness of the skin (pallor), lightheadedness and additional findings. Megaloblastic anemia has several different causes - deficiencies of either cobalamin (vitamin B12) or folate (vitamin B9) are the two most common causes. These vitamins play an essential role in the production of red blood cells.

Organizations related to Anemia, Megaloblastic
  • Anemia Institute for Research and Education
    151 Bloor Street West
    Suite 600
    Toronto, Ontario None M5S 1S4
    Phone #: 416--96-9-7431
    800 #: 877--99-2-6364
    e-mail: info@anemiainstitute.org
    Home page: http://www.anemiainstitute.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: ordr@od.nih.gov
    Home page: http://rarediseases.info.nih.gov/Default.aspx
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • NIH/National Heart, Lung and Blood Institute
    31 Center Drive MSC 2480
    Building 31A Rm 4A16
    Bethesda MD 20892-2480
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: http://www.nhlbi.nih.gov/

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Last modified Wednesday, November 26, 2008