The National Organization for Rare Disorders (NORD)

Database Subscriptions

Many libraries, schools, universities, and hospitals subscribe to NORD’s Rare Disease Database for unlimited access to reports on more than 1,200 diseases.

Index of Rare Diseases

This is the list of diseases currently covered in the Rare Disease Database.

Rare Disease Database

Search this database for reports on more than 1,200 diseases.

View sample report

Index of Organizations

This is the list of organizations in NORD’s Organizational Database.

Organizational Database

Read about more than 2,000 patient organizations and other sources of help.

NORD's
Washington Office

NORD's Washington OfficeRead about events on Capitol Hill, funding for rare-disease research, and other topics of interest from NORD's office in Washington, DC.

 



Apnea, Sleep

To purchase full-text report ($7.50):
View Cart/Checkout

The National Organization for Rare Disorders (NORD) web site, its databases, and the contents thereof are copyrighted by NORD. No part of the NORD web site, databases, or the contents may be copied in any way, including but not limited to the following: electronically downloading, storing in a retrieval system, or redistributing for any commercial purposes without the express written permission of NORD. Permission is hereby granted to print one hard copy of the information on an individual disease for your personal use, provided that such content is in no way modified, and the credit for the source (NORD) and NORD’s copyright notice are included on the printed copy. Any other electronic reproduction or other printed versions is strictly prohibited.

The information in NORD's Rare Disease Database is for educational purposes only. It should never be used for diagnostic or treatment purposes. If you have questions regarding a medical condition, always seek the advice of your physician or other qualified health professional. NORD's reports provide a brief overview of rare diseases. For more specific information, we encourage you to contact your personal physician or the agencies listed as "Resources" on this report.

Copyright 1986, 1987, 1989, 1992, 1993, 1995, 1996, 1998, 2000, 2007



Synonyms of Apnea, Sleep
  • Pediatric Obstructive Sleep Apnea

Disorder Subdivisions

  • Central Sleep Apnea
  • Mixed Sleep Apnea
  • Obstructive Sleep Apnea (Upper Airway Apnea)
  • Pickwickian Syndrome


General Discussion
Sleep apnea is a sleep disorder characterized by temporary, recurrent interruptions of breathing (respiration) during sleep. Symptoms of this disorder include periodic wakefulness during the night, excessive sleepiness during the day, and loud snoring during sleep. People with this disorder are frequently overweight. Diagnosis and treatment of sleep apnea can avoid serious medical problems that may arise as a consequence of oxygen deprivation in untreated individuals. Sleep apnea occurs in three different forms: obstructive, central, and mixed.

An individual's rate of respiration is regulated by group of nerve cells in the brain that control the rhythm of breathing in response to changing oxygen levels in the blood (respiratory drive). In some apneas, the respiratory drive is abnormal. Obstructive sleep apnea (upper airway apnea), the most common form of sleep apnea, results from the blockage of the respiratory passages during sleep. Affected individuals may struggle to breathe and experience increased respiratory effort. Respiratory drive is unaffected in people with this form of sleep apnea but the blockage prevents them from breathing normally. Obstructive apnea is more likely than central apnea to be associated with snorting and arousal from sleep.

In the rare central sleep apnea, the brain does not send adequate signals to the diaphragm and lungs during sleep, resulting in low respiratory drive. In this form of sleep apnea, breathing stops and does not resume until the oxygen-deprived brain finally sends impulses to the diaphragm and lungs. In infants, central sleep apnea is defined as lasting 20 seconds or more.

Mixed sleep apnea is a combination of improper brain signals and obstruction of the respiratory passages. In some cases, sleep apnea is referred to as "Pickwickian Syndrome." In these cases, obstructive apnea is combined with obesity and an abnormally short neck. Infantile sleep apnea affects children less than one year old, and its cause is unknown. (For more information on infantile sleep apnea, see the Related Disorders section of this report.)
.

Organizations related to Apnea, Sleep
  • American Sleep Apnea Association
    6856 Eastern Avenue, NW, Suite 203
    Washington DC 20012
    Phone #: 202-293-3650
    800 #: --
    e-mail: asaa@sleepapnea.org
    Home page: http://www.sleepapnea.org
  • American Sleep Association
    1610 14th Street NW
    Suite 300
    Rochester MN 55901
    Phone #: 507-287-6006
    800 #: --
    e-mail: asda@millcomm.com
    Home page: http://www.sleepassociation.org/
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
    Home page: http://rarediseases.info.nih.gov/GARD
  • MUMS National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Narcolepsy Network, Inc.
    110 Ripple Lane
    North Kingstown RI 02852
    Phone #: 401-667-2523
    800 #: 888-292-6522
    e-mail: narnet@narcolepsynetwork.org
    Home page: http://www.narcolepsynetwork.org
  • National Institute of Neurological Disorders and Stroke (NINDS)
    P.O. Box 5801
    Bethesda MD 20824
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: me20t@nih.gov
    Home page: http://www.ninds.nih.gov/
  • National Sleep Foundation
    1522 K Street
    Suite 500
    Washington D.C. 20005
    Phone #: 202-347-3471
    800 #: --
    e-mail: nsf@sleepfoundation.org
    Home page: http://www.sleepfoundation.org
  • Tri-State Sleep Disorders Center
    1275 East Kemper Rd.
    Cincinnati OH 45246
    Phone #: 513-671-3101
    800 #: 800-838-4322
    e-mail: ggaz@tristatesleep.com
    Home page: http://www.tristatesleep.com

ABOUT NORD .|. CONTACT NORD .|. MEMBERSHIP .|. PRIVACY POLICY .|. DISCLAIMER .|. HOME
©2009 NORD - National Organization for Rare Disorders, Inc. All rights reserved.

Last modified Wednesday, November 26, 2008