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Atrial Septal Defects

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Synonyms of Atrial Septal Defects
  • ASD
  • Atrioseptal Defects

Disorder Subdivisions

  • Ostium Primum Defect (endocardial cushion defects included)
  • Ostium Secundum Defect
  • Sinus Venosus


General Discussion
Atrial septal defects (ASDs) are a group of rare disorders of the heart that are present at birth (congenital) and involve a hole in the wall (septum) that separates the two upper-chambers (atria) of the heart.

Normally the heart has four chambers: two upper chambers known as atria that are separated from each other by a fibrous partition known as the atrial septum and two lower chambers known as ventricles that are separated from each other by the ventricular septum. Valves connect the atria (left and right) to their respective ventricles. A small opening between the two atria (foramen ovale) is present at birth. Shortly after birth, the atrial septum gradually grows and seals this opening. In infants with atrial septal defects, the atrial septum may not close properly or may be malformed during fetal development. In these disorders, the opening (called patent foramen ovale) between the atria persists long after it should be closed, resulting in an increase in the workload on the right side of the heart and excessive blood flow to the lungs.

Initially, the symptoms associated with atrial septal defects may be absent or so mild that they may go unnoticed. Frequently this disorder is not recognized until school age or even adulthood. In adults with undetected atrial septal defects, various respiratory problems and/or heart failure may develop.

Several forms of atrial septal defects are recognized. They are classified according to their location in the septum. The term primum refers to defects that are in the lower part of the septum. The term secundum refers to defects that are located in the middle of the septum, and the term sinus venosus refers to defects in the upper part of the septum.
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Organizations related to Atrial Septal Defects
  • American Heart Association
    7272 Greenville Avenue
    Dallas TX 75231-4596
    Phone #: 214-373-6300
    800 #: 800-242-8721
    e-mail: Review.personal.info@heart.org
    Home page: http://www.americanheart.org
  • American Lung Association
    1301 Pennsylvania Ave. NW
    Washington DC 20004
    Phone #: 202-785-3355
    800 #: 800-586-4872
    e-mail: info@lungusa.org
    Home page: http://www.lungusa.org
  • Congenital Heart Information Network (C.H.I.N.)
    101 N Washington Ave, Suite 1A 101 N Washington Ave, Suite 1A
    Margate City NJ 08402-1195
    Phone #: 609-822-1572
    800 #: --
    e-mail: mb@tchin.org
    Home page: http://www.tchin.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
    Home page: http://rarediseases.info.nih.gov/GARD
  • Kids With Heart National Association for Children's Heart Disorders, Inc.
    P.O Box 12504
    Green Bay WI 54307-2504
    Phone #: 920-498-0058
    800 #: 800-538-5390
    e-mail: michelle@kidswithheart.org
    Home page: http://www.kidswithheart.org
  • Little Hearts, Inc.
    P.O. Box 171
    110 Court Street, Suite 3A
    Cromwell CT 06416
    Phone #: 860-635-0006
    800 #: 866-435-4673
    e-mail: info@littlehearts.org
    Home page: http://www.littlehearts.org
  • MUMS National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • March of Dimes Birth Defects Foundation
    1275 Mamaroneck Avenue
    White Plains NY 10605
    Phone #: 914-997-4488
    800 #: 888-663-4637
    e-mail: Askus@marchofdimes.com
    Home page: http://www.marchofdimes.com
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A

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Last modified Tuesday, September 07, 2010