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Autoimmune Blistering Diseases

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The National Organization for Rare Disorders (NORD) web site, its databases, and the contents thereof are copyrighted by NORD. No part of the NORD web site, databases, or the contents may be copied in any way, including but not limited to the following: electronically downloading, storing in a retrieval system, or redistributing for any commercial purposes without the express written permission of NORD. Permission is hereby granted to print one hard copy of the information on an individual disease for your personal use, provided that such content is in no way modified, and the credit for the source (NORD) and NORD’s copyright notice are included on the printed copy. Any other electronic reproduction or other printed versions is strictly prohibited.

The information in NORD's Rare Disease Database is for educational purposes only. It should never be used for diagnostic or treatment purposes. If you have questions regarding a medical condition, always seek the advice of your physician or other qualified health professional. NORD's reports provide a brief overview of rare diseases. For more specific information, we encourage you to contact your personal physician or the agencies listed as "Resources" on this report.

Copyright 2008

NORD is very grateful to Peter Marinkovich, MD, Associate Professor, Director, Bullous Disease Clinic, Department of Dermatology, Stanford University School of Medicine, Center for Clinical Sciences Research, for assistance in the preparation of this report.

Synonyms of Autoimmune Blistering Diseases

Disorder Subdivisions

  • Epidermolysis Bullosa Acquista
  • IgA-Mediated Bullous Dermatoses
  • Pemphigoid
  • Pemphigus


General Discussion
Autoimmune blistering diseases are a group of disorders in which the body mistakenly attacks healthy tissue, causing blistering lesions that primarily affect the skin and mucous and membranes. In autoimmune blistering diseases, antibodies mistakenly attack proteins that are essential for the layers of skin to stick (adhere) together. The specific symptoms and severity of blistering diseases vary from one person to another, even among individuals with the same disorder. In some cases, blistering lesions can cover a significant portion of the skin. Although there is no cure for autoimmune blistering diseases, they can often be controlled with treatment. In other cases, autoimmune blistering diseases if left untreated can eventually cause life-threatening complications. In recent years, new insight into the causes and development of these disorders has led to research into new therapies such as the development of drugs that target the specific antibodies which cause the symptoms of these diseases. NORD has individual reports on many of the specific disorders classified as autoimmune blistering diseases. For more information, choose the specific disease name as your search term in the Rare Disease Database.
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Organizations related to Autoimmune Blistering Diseases
  • American Autoimmune Related Diseases Association, Inc.
    22100 Gratiot Avenue
    Eastpointe MI 48021
    Phone #: 586-776-3900
    800 #: 800-598-4668
    e-mail: aarda@aarda.org
    Home page: http://www.aarda.org/
  • Australasian Blistering Diseases Foundation
    St. George Hospital
    Department of Dermatology
    Gray Street
    KOGARAH NSW 2217
    None None None
    Phone #: 02 -911-3 2543
    800 #: N/A
    e-mail: N/A
    Home page: N/A
  • AutoImmunity Community
    None
    None None None
    Phone #: (91-9) -552-9057
    800 #: N/A
    e-mail: moderator@autoimmunitycommunity.org
    Home page: http://www.autoimmunitycommunity.org
  • Autoimmune Information Network, Inc
    PO Box 4121
    Brick NJ 08723
    Phone #: 732-664-9259
    800 #: N/A
    e-mail: autoimmunehelp@aol.com
    Home page: http://www.aininc.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
    Home page: http://rarediseases.info.nih.gov/GARD
  • International Pemphigus & Pemphigoid Foundation International Pemphigus & Pemphigoid Foundation
    2701 Cottage Way
    Suite 16
    Sacramento CA 95825
    Phone #: 916-922-1298
    800 #: --
    e-mail: pemphigus@pemphigus.org
    Home page: http://www.pemphigus.org
  • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
    1 AMS Circle
    Bethesda MD 20892-3675
    Phone #: 301-495-4484
    800 #: 877-226-4267
    e-mail: NIAMSinfo@mail.nih.gov
    Home page: http://www.niams.nih.gov/Health_Info

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Last modified Wednesday, November 26, 2008