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 Read about events on Capitol Hill, funding for rare-disease research, and other topics of interest from NORD's office in Washington, DC.
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"Resources" on this report.
Copyright 1984, 1985, 1987, 1990, 1992, 1997, 1999, 2007, 2008
NORD is very grateful to Adam Mezoff, MD, Professor of Pediatrics, Wright State University, and Director, Pediatric GI & Nutrition, Dayton Children's Hospital, for assistance in the preparation of this report.
Synonyms of Cri du Chat Syndrome
- 5p- syndrome
- cat’s cry syndrome
- CdCS
- Lejeune syndrome
Disorder Subdivisions
General Discussion
Cri du chat syndrome (CdCS) is a rare genetic disorder in which a variable portion of chromosome 5 is missing or deleted (monosomic). Symptoms vary greatly from case to case depending upon the exact size and location of the deleted genetic material. Common symptoms include a distinctive cry that resembles the mewing of a cat, characteristic facial features, slow growth, and microcephaly, a condition that indicates that head circumference is smaller than would be expected for an infant’s age and sex. Affected children also exhibit delays in the acquisition of skills requiring the coordination of muscular and mental activities (psychomotor retardation) and moderate to severe mental retardation. Additional symptoms affecting different organ systems of the body can also potentially occur. Most cases are thought arise from spontaneous (de novo) errors very early in embryonic development.
Organizations related to Cri du Chat Syndrome
- 5p- Society
PO Box 268
Lakewood CA 90714-0268
Phone #: 562-804-4506
800 #: 888-970-0777
e-mail: director@fivepminus.org
Home page: http://www.fivepminus.org
- Arc (a national organization on mental retardation)
1010 Wayne Ave
Suite 650
Silver Spring MD 20910
Phone #: 301-565-3842
800 #: 800-433-5255
e-mail: info@thearc.org
Home page: http://www.thearc.org/
- Chromosome Disorder Outreach, Inc.
P.O. Box 724
Boca Raton FL 33429-0724
Phone #: 561-395-4252
800 #: N/A
e-mail: info@chromodisorder.org
Home page: http://www.chromodisorder.org
- Cri Du Chat Syndrome Support Group
PO Box 3408
Norwich Intl NR3 3WE
Phone #: 084-5 0-942725
800 #: --
e-mail: office@criduchat.org.uk
Home page: http://www.criduchat.org.uk/
- Department of Human Genetics/Cri du Chat
Virginia Commonwealth University
Medical College of Virginia
P.O. Box 980033
Richmond VA 23298-0033
Phone #: 804-828-8116
800 #: --
e-mail: N/A
Home page: N/A
- Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg MD 20898-8126
Phone #: 301-251-4925
800 #: 888-205-2311
e-mail: ordr@od.nih.gov
Home page: http://rarediseases.info.nih.gov/Default.aspx
- MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay WI 54301-1243
Phone #: 920-336-5333
800 #: 877-336-5333
e-mail: mums@netnet.net
Home page: http://www.netnet.net/mums/
- Madisons Foundation
PO Box 241956
Los Angeles CA 90024
Phone #: 310-264-0826
800 #: N/A
e-mail: getinfo@madisonsfoundation.org
Home page: http://www.madisonsfoundation.org
- March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains NY 10605
Phone #: 914-997-4488
800 #: 888-663-4637
e-mail: Askus@marchofdimes.com
Home page: http://www.marchofdimes.com
- UNIQUE - Rare Chromosome Disorder Support Group
P.O. Box 2189
Caterham
Surrey Intl CR3 5GN
Phone #: 44 -0 1-883 330766
800 #: --
e-mail: info@rarechromo.org
Home page: http://www.rarechromo.org
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