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Glioblastoma Multiforme

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Copyright 1986, 1987, 1988, 1989, 1996, 1997, 1998, 1999, 2000, 2002, 2004, 2007

NORD is very grateful to Amy B Heimberger, MD, Associate Professor of Neurosurgery, University of Texas MD Anderson Cancer Center, for assistance in the preparation of this report.

Synonyms of Glioblastoma Multiforme
  • astrocytoma, grade IV
  • GBM

Disorder Subdivisions



General Discussion
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor. These tumors are often aggressive and infiltrate surrounding brain tissue. GBMs arise from glial cells, which are cells that form the tissue that surrounds and protects other nerve cells found within the brain and spinal cord. GBMs are mainly composed of star-shaped glial cells known as astrocytes. The general term glioma includes any type of brain tumor such as astrocytoma and oligodendroglioma that arise from glial cells.

Astrocytomas are classified according to a grading system developed by the World Health Organization (WHO). Astrocytomas come in four grades based upon how fast the cells are reproducing and that likelihood that they will infiltrate nearby tissue. Grades I or II astrocytomas are nonmalignant and may be referred to as low-grade. Grades III and IV astrocytomas are malignant and may be referred to as high-grade astrocytomas. Grade III astrocytomas are known as anaplastic astrocytomas. Grade IV astrocytomas are known as glioblastoma multiforme.

Organizations related to Glioblastoma Multiforme
  • American Brain Tumor Association
    2720 River Road
    Suite 146
    Des Plaines IL 60018
    Phone #: 847-827-9910
    800 #: 800-886-2282
    e-mail: info@abta.org
    Home page: http://www.abta.org
  • American Cancer Society, Inc.
    1599 Clifton Road NE
    Atlanta GA 30329
    Phone #: 404-320-3333
    800 #: 800-227-2345
    e-mail: N/A
    Home page: http://www.cancer.org
  • Candlelighters Childhood Cancer Foundation
    P.O. Box 498
    Kensington MD 20895-0498
    Phone #: 301-962-3520
    800 #: 800-366-2223
    e-mail: staff@candlelighters,org
    Home page: http://www.candlelighters.org
  • Friends of Cancer Research
    2231 Crystal Drive
    Suite 200
    Arlington VA 22202
    Phone #: 703-302-1503
    800 #: N/A
    e-mail: info@focr.org
    Home page: http://www.focr.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: ordr@od.nih.gov
    Home page: http://rarediseases.info.nih.gov/Default.aspx
  • Harvard Brain Tissue Resource Center
    McLean Hospital
    115 Mill Street
    Belmont MA 02478
    Phone #: 617-855-2400
    800 #: 800-272-4622
    e-mail: hbtrc@mclean.harvard.edu
    Home page: http://www.brainbank.mclean.org
  • Lance Armstrong Foundation
    2201 E. Sixth Street
    Austin TX 78702
    Phone #: 512-236-8820
    800 #: 877-236-8820
    e-mail: media@livestrong.org
    Home page: http://www.livestrong.org
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • National Brain Tumor Society
    124 Watertown Street, Suite 2D
    Watertown MA 02472
    Phone #: 617-924-9997
    800 #: (80-0) -770-8287
    e-mail: info@braintumor.org
    Home page: http://www.braintumor.org
  • National Cancer Institute
    6116 Executive Blvd, MSC 8322, Room 3036A
    Bethesda MD 20892-8322
    Phone #: 301-435-3848
    800 #: 800-422-6237
    e-mail: N/A
    Home page: http://www.cancer.gov
  • Pediatric Brain Tumor Foundation
    302 Ridgefield Court
    Asheville NC 28806
    Phone #: 828-665-6891
    800 #: 800-253-6530
    e-mail: N/A
    Home page: http://www.pbtfus.org
  • Wellness Community
    919 18th Street N.W.
    Suite 54
    Washington DC 20006
    Phone #: 202-659-9709
    800 #: 888-793-9355
    e-mail: help@thewellnesscommunity.org
    Home page: http://www.thewellnesscommunity.org

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Last modified Wednesday, November 26, 2008