NORD's
Washington Office
 Read about events on Capitol Hill, funding for rare-disease research, and other topics of interest from NORD's office in Washington, DC.
|
|
|
The National Organization for Rare Disorders (NORD) web site, its databases,
and the contents thereof are copyrighted by NORD. No part of the NORD web
site, databases, or the contents may be copied in any way, including but not
limited to the following: electronically downloading, storing in a retrieval
system, or redistributing for any commercial purposes without the express
written permission of NORD. Permission is hereby granted to print one hard
copy of the information on an individual disease for your personal use,
provided that such content is in no way modified, and the credit for the
source (NORD) and NORD’s copyright notice are included on the printed copy.
Any other electronic reproduction or other printed versions is strictly
prohibited.
The information in NORD's Rare Disease Database is for educational purposes only. It
should never be used for diagnostic or treatment purposes. If you have questions regarding
a medical condition, always seek the advice of your physician or other qualified health
professional. NORD's reports provide a brief overview of rare diseases. For more specific
information, we encourage you to contact your personal physician or the agencies listed as
"Resources" on this report.
Copyright 1989, 1991, 1992, 1993, 1997, 1999, 2002, 2003, 2004, 2005, 2007, 2009
NORD is very grateful to Mary C. Dinauer, MD, PhD, Department of Pediatrics (Hematology/Oncology), Microbiology/Immunology, and Medical and Molecular Genetics, Herman B Wells Center for Pediatric Research, Riley Hospital for Children, Indiana University School of Medicine, for assistance in the preparation of this report.
Synonyms of Granulomatous Disease, Chronic
- CGD
- Chronic Dysphagocytosis
- Chronic Granulomatous Disease
- Congenital Dysphagocytosis
- Fatal Granulomatous Disease of Childhood
- Granulomatosis, Chronic, Familial
- Granulomatosis, Septic, Progressive
- Impotent Neutrophil Syndrome
Disorder Subdivisions
General Discussion
Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (neutrophils, monocytes, macrophages, eosinophils). The disorder is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones may occur along with swollen areas of inflamed tissues known as granulomas that can be widely distributed. Symptoms usually begin in infancy or childhood. Individuals with mild forms of the disorder may not develop symptoms until the teens or adulthood. Chronic granulomatous disease is a genetic disorder and is caused by inherited defects in an important enzyme in white blood cells that manufactures oxidants for microbial killing.
Organizations related to Granulomatous Disease, Chronic
- Chronic Granulomatous Disease Association, Inc.
c/o Mary Hurley
2616 Monterey Road
San Marino CA 91108-1646
Phone #: 626-441-4118
800 #: --
e-mail: cgda@socal.rr.com
Home page: http://www.cgdassociation.org
- Chronic Granulomatous Disease Registry
c/o Immune Deficiency Foundation
40 W. Chesapeake Avenue
Suite 308
Towson MD 21204
Phone #: 410-321-6647
800 #: 800-296-4433
e-mail: idf@primaryimmune.org
Home page: http://www.primaryimmune.org
- Chronic Granulomatous Disorder (CGD) Research Trust
PO Box 6478
Wimborne Intl BH21 9BU
Phone #: 017-25 -517 977
800 #: N/A
e-mail: cgd@cgdrt.co.uk
Home page: http://www.cgd.org.uk
- European Society for Immunodeficiencies (ESID)
c/o Dr. Bodo Grimbacher (ESID Board Member)
Division of Rheumatology and Clinical Immunology
Department of Medicine, University Hospital Freiburg
Hugstetter Strasse 55
Freiburg None D-79106
Phone #: +31- 73--6992965
800 #: N/A
e-mail: info@esid.org
Home page: http://www.esid.org
- Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg MD 20898-8126
Phone #: 301-251-4925
800 #: 888-205-2311
e-mail: ordr@od.nih.gov
Home page: http://rarediseases.info.nih.gov/Default.aspx
- Immune Deficiency Foundation
40 West Chesapeake Avenue
Suite 308
Towson MD 21204
Phone #: 410-321-6647
800 #: 800-296-4433
e-mail: idf@primaryimmune.org
Home page: http://www.primaryimmune.org
- International Patient Organization for Primary Immunodeficiencies
Firside
Main Road
Downderry
Cornwall None PL11 3LE
Phone #: 44 -150-3 250 668
800 #: --
e-mail: david@ipopi.org
Home page: http://www.ipopi.org/
- Jeffrey Modell Foundation
747 Third Avenue
34th Floor
New York NY 10017
Phone #: 212-819-0200
800 #: 866-469-6474
e-mail: info@jmfworld.org
Home page: http://www.info4pi.org
- NIH/National Institute of Allergy and Infectious Diseases
6610 Rockledge Drive
MSC 6612
Bethesda MD 20892-6612
Phone #: 301-496-5717
800 #: --
e-mail: N/A
Home page: http://www.niaid.nih.gov/
|
|
