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Human Granulocytic Ehrlichiosis (HGE)

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Synonyms of Human Granulocytic Ehrlichiosis (HGE)
  • HGE
  • Human Ehrlichial Infection, Human Granulocytic Type

Disorder Subdivisions



General Discussion
Human Granulocytic Ehrlichiosis (HGE) is a rare infectious disease that belongs to a group of diseases known as the Human Ehrlichioses. The Ehrlichioses are infectious diseases caused by bacteria in the "Ehrlichia" family. Several forms of Human Ehrlichial infection have been identified including Human Granulocytic Ehrlichiosis (HGE), Sennetsu Fever, and Human Monocytic Ehrlichiosis (HME). Though caused by different strains of Ehrlichia bacteria, the disorders are all characterized by similar symptoms.

The symptoms of Human Granulocytic Ehrlichiosis (HGE) may include a sudden high fever, headache, muscle aches (myalgia), chills, and a general feeling of weakness and fatigue (malaise) within a week or so after initial infection. In most cases, abnormal laboratory findings may occur including an abnormally low number of circulating blood platelets (thrombocytopenia), a decrease in white blood cells (leukopenia), and an abnormal increase in the level of certain liver enzymes (hepatic transaminases). In some cases, symptoms may progress to include nausea, vomiting, cough, diarrhea, loss of appetite (anorexia), and/or confusion. If Human Granulocytic Ehrlichiosis is left untreated, life-threatening symptoms, such as kidney failure and/or respiratory problems, may develop in some cases. Human Granulocytic Ehrlichiosis is caused by a bacterium of the Ehrlichiosis family that has not yet been named. The Ehrlichial bacterium is carried and transmitted by certain ticks (vectors), such as the deer tick (Ixodes dammini) and the American dog tick (Dermacentor variabilis).

Organizations related to Human Granulocytic Ehrlichiosis (HGE)
  • American Lyme Disease Foundation, Inc.
    PO Box 684
    Somers NY 10589
    Phone #: N/A
    800 #: N/A
    e-mail: inquire@aldf.com
    Home page: http://www.aldf.com
  • Centers for Disease Control and Prevention
    1600 Clifton Road NE
    Atlanta GA 30333
    Phone #: 404-639-3534
    800 #: 800-311-3435
    e-mail: http://www.cdc.gov/netinfo.htm
    Home page: http://www.cdc.gov/
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: ordr@od.nih.gov
    Home page: http://rarediseases.info.nih.gov/Default.aspx
  • Lyme Disease Foundation
    P.O. Box 332
    Tolland CT 06084-0332
    Phone #: 860-870-0070
    800 #: 800-886-5963
    e-mail: info@lyme.org
    Home page: http://www.lyme.org
  • NIH/National Institute of Allergy and Infectious Diseases
    6610 Rockledge Drive
    MSC 6612
    Bethesda MD 20892-6612
    Phone #: 301-496-5717
    800 #: --
    e-mail: N/A
    Home page: http://www.niaid.nih.gov/
  • World Health Organization (WHO) Regional Office for the Americas (AMRO)
    Pan American Health Organization (PAHO)
    525 23rd Street NW
    Washington DC 20037
    Phone #: 202-974-3000
    800 #: --
    e-mail: postmaster@paho.org
    Home page: http://www.who.ch/

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Last modified Wednesday, November 26, 2008