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Kernicterus

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Synonyms of Kernicterus
  • Bilirubin Encephalopathy

Disorder Subdivisions



General Discussion
Kernicterus is a rare neurological disorder characterized by excessive levels of bilirubin in the blood (hyperbilirubinemia) during infancy. Bilirubin is an orange-yellow bile pigment that is a byproduct of the natural breakdown of hemoglobin in red blood cells (hemolysis). Toxic levels of bilirubin may accumulate in the brain, potentially resulting in a variety of symptoms and physical findings. These symptoms may include lack of energy (lethargy), poor feeding habits, fever, and vomiting. Affected infants may also experience the absence of certain reflexes (e.g., Moro reflex, etc.); mild to severe muscle spasms including those in which the head and heels are bent backward and the body bows forward (opisthotonus); and/or uncontrolled involuntary muscle movements (spasticity). In some cases, infants with kernicterus may develop life-threatening complications.

Organizations related to Kernicterus
  • American Liver Foundation
    75 Maiden Lane
    Suite 603
    New York NY 10038
    Phone #: 212-668-1000
    800 #: 800-465-4837
    e-mail: info@liverfoundation.org
    Home page: http://www.liverfoundation.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: ordr@od.nih.gov
    Home page: http://rarediseases.info.nih.gov/Default.aspx
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • March of Dimes Birth Defects Foundation
    1275 Mamaroneck Avenue
    White Plains NY 10605
    Phone #: 914-997-4488
    800 #: 888-663-4637
    e-mail: Askus@marchofdimes.com
    Home page: http://www.marchofdimes.com
  • NIH/National Institute of Diabetes, Digestive & Kidney Diseases
    Endocrine Diseases Metabolic Diseases Branch
    2 Information Way
    Bethesda MD 20892-3570
    Phone #: 301-654-3810
    800 #: --
    e-mail: NDDIC@info.niddk.nih.gov
    Home page: http://www.niddk.nih.gov
  • Parents of Infants and Children with Kernicterus
    One Superior Place
    Suite 2410
    Chicago IL 60610
    Phone #: 312-274-9695
    800 #: --
    e-mail: karendixon@pickonline.org
    Home page: http://www.PICKonline.org

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Last modified Wednesday, November 26, 2008