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"Resources" on this report.
Copyright 1986, 1989, 1990, 1993, 1994, 1996, 1997, 2003
Synonyms of Machado-Joseph Disease
- Autosomal Dominant Spinocerebellar Degeneration
- Azorean Neurologic Disease
- Joseph Disease
- Machado Disease
- MJD
- Nigrospinodentatal Degeneration
- Spinocerebellar Ataxia Type III (SCA 3)
- Striatonigral Degeneration, Autosomal Dominant Type
Disorder Subdivisions
- Machado-Joseph Disease Type III (MJD-III)
- Machado-Joseph Disease Type II (MJD-II)
- Machado-Joseph Disease Type I (MJD-I)
General Discussion
Machado-Joseph Disease (MJD-III), also called spinocerebellar ataxia type III, is a rare, inherited, ataxia (lack of muscular control) affecting the central nervous system and characterized by the slow degeneration of particular areas of the brain called the hindbrain. Patients with MJD may eventually become crippled and/or paralyzed but their intellect remains intact. The onset of symptoms of MJD varies from early teens to late adulthood.
Three forms of Machado-Joseph Disease are recognized: Types MJD-I, MJD-II, and MJD-III. The differences in the types of MJD relate to the age of onset and severity. Earlier onset usually produces more severe symptoms.
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Organizations related to Machado-Joseph Disease
- Canadian Association for Familial Ataxias - Claude St-Jean Foundation
3800 Radisson Street
Suite 110
Montreal
Quebec Intl H1M 1X6
Phone #: (51-4) -321-8684
800 #: --
e-mail: ataxie@lacaf.org
Home page: http://www.lacaf.org
- Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg MD 20898-8126
Phone #: 301-251-4925
800 #: 888-205-2311
e-mail: ordr@od.nih.gov
Home page: http://rarediseases.info.nih.gov/Default.aspx
- International Joseph Disease Foundation, Inc.
P.O. Box 994268
Redding CA 96099
Phone #: 530-246-4722
800 #: --
e-mail: MJD@ijdf.net
Home page: N/A
- MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay WI 54301-1243
Phone #: 920-336-5333
800 #: 877-336-5333
e-mail: mums@netnet.net
Home page: http://www.netnet.net/mums/
- Madisons Foundation
PO Box 241956
Los Angeles CA 90024
Phone #: 310-264-0826
800 #: N/A
e-mail: getinfo@madisonsfoundation.org
Home page: http://www.madisonsfoundation.org
- National Ataxia Foundation
2600 Fernbrook Lane, Suite 119
Minneapolis MN 55447-4752
Phone #: 763-553-0020
800 #: --
e-mail: naf@ataxia.org
Home page: http://www.ataxia.org
- National Institute of Neurological Disorders and Stroke (NINDS)
P.O. Box 5801
Bethesda MD 20824
Phone #: 301-496-5751
800 #: 800-352-9424
e-mail: me20t@nih.gov
Home page: http://www.ninds.nih.gov/
- Rosenberg, Roger N., M.D.
Department of Neurology and Physiology
University of Texas Southwestern Medical School
5323 Harry Hines Blvd.
Dallas TX 75235-9036
Phone #: 214-688-4800
800 #: --
e-mail: N/A
Home page: N/A
- WE MOVE (Worldwide Education and Awareness for Movement Disorders)
204 West 84th Street
New York NY 10024
Phone #: 212-875-8312
800 #: N/A
e-mail: wemove@wemove.org
Home page: http://www.wemove.org
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