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Sinonasal Undifferentiated Carcinoma

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Copyright 2004

NORD is grateful to Andrew Martin, medical student, and Raja Mudad, MD, Associate Professor and Associate Section Chief of Medicine: Hematology-Oncology, Tulane Cancer Center; Director of Hematology-Oncology, Veterans Administration Medical Center, New Orleans, for assistance in the preparation of this report.

Synonyms of Sinonasal Undifferentiated Carcinoma
  • No synonyms found

Disorder Subdivisions

  • No synonyms found


General Discussion
Sinonasal undifferentiated carcinoma (SNUC) is a rare cancer of the nasal cavity and/or paranasal sinuses. Initial symptoms range from bloody nose, runny nose, double vision, and bulging eye to chronic infections and nasal obstruction. It has been associated with several types of papilloma in the nasal cavity, which are benign, but can give rise to malignancy. Prior irradiation for other cancers has been associated with the development of SNUC in a number of cases, and has been associated with a genetic mutation known to be associated with cancer development. Most patients have not had prior irradiation, and no other causes have demonstrated to be significant, though some studies have found that woodworkers and nickel factory workers are generally more susceptible to sinonasal malignancy of all types.

Organizations related to Sinonasal Undifferentiated Carcinoma
  • American Cancer Society, Inc.
    1599 Clifton Road NE
    Atlanta GA 30329
    Phone #: 404-320-3333
    800 #: 800-227-2345
    e-mail: N/A
    Home page: http://www.cancer.org
  • Cancer Support Community
    919 18th Street N.W.
    Suite 54
    Washington DC 20006
    Phone #: 202-659-9709
    800 #: 888-793-9355
    e-mail: N/A
    Home page: www.cancersupportcommunity.org
  • Friends of Cancer Research
    2231 Crystal Drive
    Suite 200
    Arlington VA 22202
    Phone #: 703-302-1503
    800 #: N/A
    e-mail: info@focr.org
    Home page: http://www.focr.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
    Home page: http://rarediseases.info.nih.gov/GARD
  • Lance Armstrong Foundation
    2201 E. Sixth Street
    Austin TX 78702
    Phone #: 512-236-8820
    800 #: 877-236-8820
    e-mail: media@livestrong.org
    Home page: http://www.livestrong.org
  • National Cancer Institute
    6116 Executive Blvd, MSC 8322, Room 3036A
    Bethesda MD 20892-8322
    Phone #: 301-435-3848
    800 #: 800-422-6237
    e-mail: cancergovstaff@mail.nih.gov
    Home page: http://www.cancer.gov
  • Support for People with Oral and Head and Neck Cancer, Inc.
    P.O. Box 53
    Locust Valley NY 11560-0053
    Phone #: 516-759-5333
    800 #: 800-377-0928
    e-mail: info@spohnc.org
    Home page: http://www.spohnc.org

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Last modified Wednesday, November 26, 2008